Author's response to reviews Title: Candidemia in the Critically Ill: Initial Therapy and Outcome in Mechanically Ventilated Patients Authors:

نویسندگان

  • Marcela A Ferrada
  • Andrew A Quartin
  • Daniel H Kett
  • Michele I Morris
چکیده

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Title: Candidemia in the Critically Ill: Initial Therapy and Outcome in Mechanically Ventilated Patients

Author's response to reviews: Highlighted version with change in several lines of text, noted to be incorrect when revision viewed on PDF.

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Candidemia in the critically ill: initial therapy and outcome in mechanically ventilated patients

BACKGROUND Mortality among critically ill patients with candidemia is very high. We sought to determine whether the choice of initial antifungal therapy is associated with survival among these patients, using need for mechanical ventilatory support as a marker of critical illness. METHODS Cohort analysis of outcomes among mechanically ventilated patients with candidemia from the 24 North Amer...

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Pharmacokinetics Alterations of Midazolam Infusion versus Bolus Administration in Mechanically Ventilated Critically Ill Patients

There is no randomized study carried out in order to compare their pharmacokinetic parameters although midazolam, as a sedative, has been widely administered via continuous infusion as well as intermittent bolus doses in mechanically ventilated critically ill patients. We prospectively investigated the effect of these two principal methods on pharmacokinetic parameters in 23 of mentioned patien...

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تاریخ انتشار 2013